Duff has caused Homer a lot of trouble in the past and one memory that's best to forget is April folls day a few years back. Homer had pulled an April fool on Bart and Bart needed a way to get back at Homer.
So he shook up a can of Duff and put it in the fridge then he turned up the heating so Homer got hot and needed a drink. Homer when to the fridge and took the can of Duff. He opened it and the house exploded and Homer was sent in to a coma. He was in a coma for ages. When he finally came out of the coma his heart moniter had pictures of Bart going accross and he awoke and grabbed
Bart by the neck and throttled him.